Breast Cancer Research

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Breast Cancer Research

This section contains books on the latest developments in breast cancer research.

Breakthrough : The Race to Find the Breast Cancer Gene by Kevin Davies and Michael White

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Kevin Davies, the editor of the journal Nature Genetics, and Michael White, a science journalist, have chronicled the search for BRCA1, the gene for "heritable" breast cancer. Though just 5 to 10 percent of the 183,000 cases diagnosed each year can be linked to this gene, scientists hope to find a connection between heritable and the more common "sporadic" breast cancer caused by genetic mutations. Based on the findings of Mary-Claire King at U.C. Berkeley, Francis Collins, the director of the Human Genome Project, and Mark Skolnick, cofounder of the Utah-based Myriad Genetics, Breakthrough applauds the discovery of BRCA1, but cautions against presuming it a "quick fix."

Published January 1996, ISBN: 0471120251
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Her-2: The Making of Herceptin, A Revolutionary Treatment for Breast Cancer by Robert Bazell and Amy Bernstein

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The dramatic account of a remarkable new breast cancer drug, from its creation to the moving tales of women whose lives it is saving. The chief correspondent of NBC News, Robert Bazell presents the riveting account of how this drug moved from the lab to the bedside. Bazell presents a riveting account of how Herceptin was born. Her-2 is a story of dramatic discoveries and strong personalities, showing the combination of scientific investigation, money, politics, ego, corporate decisions, patient activism, and luck involved in moving this groundbreaking drug from the lab to a patient's bedside. Bazell's deft portraits introduce us to the remarkable people instrumental in Herceptin's history. And throughout there are the stories of the heroic women with advanced breast cancer who volunteered for the trials, risking what time they had left on an unproven treatment. Meticulously researched, written with clarity and compassion, Her-2 is masterly reporting on cutting-edge science.

Published January 1998, ISBN: 067945702X
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One Renegade Cell: How Cancer Begins by Robert A. Weinberg, PhD

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Dr. Weinberg, director of the Oncology Research Laboratory at the Whitehead Institute and professor of Biology at the Massachusetts Institute of Technology (MIT), has been at the forefront of cancer research for over a decade.  In One Renegade Cell, Dr. Weinberg presents the historical discovery of cancer and gradually introduces the intricacies and complications of the genes and proteins involved.  The language of the book is straightforward and suitable for the both the general reader and the medical professional. 

Published in October 1999, ISBN: 0465072763
Hardcover also available, ISBN: 0465072755
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Tamoxifen and Breast Cancer by Michael W. DeGregorio and Valerie J. Wiebe

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This 112 page book discusses the benefits, risks, and limitations of breast cancer treatment with the drug tamoxifen. For this revised edition, the authors have added new information regarding the use of tamoxifen, including the results of the first Breast Cancer Prevention Trial (BCPT). In addition to tamoxifen, the authors discuss the use of the drug raloxifene to prevent breast cancer, hormone replacement therapy, new biologic agents, and other preventive strategies.

Published in October 1999, ISBN: 0300079516 (hardback), ISBN: 0300059922 (paperback)

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Tamoxifen for the Treatment and Prevention of Breast Cancer by V. Craig Jordan, PhD, and Nancy Brinker

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Distinguished physicians, scientists, breast cancer advocates, and breast cancer survivors answer a multitude of questions about tamoxifen in this highly informative book on the treatment and prevention of breast cancer. Written for both the clinician and patient, this book is a premier source of information for anyone wanting to learn more about the highly publicized drug, tamoxifen.

Published in February 1999, ISBN: 1891483005
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Tamoxifen: New Hope in the Fight Against Breast Cancer by John F. Kessler MD, and Greg A. Annussek

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In this comprehensive, accessible medical guide, Dr. John Kessler, MD, provides answers to the critical questions every woman should ask before considering preventive therapy or cancer treatment with the drug tamoxifen. Questions include: who should consider themselves at high risk of developing breast cancer, do the risks of breast cancer out weight the risks of taking tamoxifen, how does tamoxifen compare with other prevention therapies, what are the side effects of tamoxifen, and how long should women take tamoxifen.

Published in April 1999, ISBN: 038081028X
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